{
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  "Package": "rnaCrosslinkOO",
  "Type": "Package",
  "Title": "Analysis of RNA Crosslinking Data",
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  "Authors@R": "c(person(\"Jonathan\", \"Price\", \nemail=\"jlp76@cam.ac.uk\",\nrole=c(\"aut\",\"cre\"),\ncomment = c(ORCID = \"0000-0001-6554-5667\")),\nperson(\"Andrew\",\n\"Lim\",\nemail=\"ajhl3@cam.ac.uk\",\nrole=c(\"ctb\")))",
  "Maintainer": "Jonathan Price <jlp76@cam.ac.uk>",
  "Description": "Analysis of RNA crosslinking data for RNA structure\nprediction. The package is suitable for the analysis of RNA\nstructure cross-linking data and chemical probing data.",
  "License": "GPL-3",
  "Encoding": "UTF-8",
  "BugReports": "https://github.com/JLP-BioInf/rnaCrosslinkOO/issues",
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  "Collate": "'rnaCrosslinkOO.R' 'rnaCrosslinkDataSet.R'\n'clusterrnaCrosslink.R'\n'clusterrnaCrosslinkMethodsAndHelpers.R'\n'commonHelpersAndMethods.R' 'commonStatsAndPlots.R'\n'foldrnaCrosslink.R' 'foldrnaCrosslinkMethodsAndHelpers.R'\n'genericMethods.R' 'rnaCrosslinkDataSetMethodsAndHelpers.R'\n'rnaCrosslinkOO-package.R' 'rnaCrosslinkQC.R'",
  "VignetteBuilder": "knitr",
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  "Packaged": {
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  "Repository": "https://jlp-bioinf.r-universe.dev",
  "Date/Publication": "2026-05-14 14:37:25 UTC",
  "RemoteUrl": "https://github.com/jlp-bioinf/rnacrosslinkoo",
  "RemoteRef": "HEAD",
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  "Author": "Jonathan Price [aut, cre] (ORCID:\n<https://orcid.org/0000-0001-6554-5667>),\nAndrew Lim [ctb]",
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  "_tags": [],
  "_topics": [
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    "clusterGrangesList",
    "clusterGrangesList<-",
    "clusterNumbers",
    "clusterrnaCrosslink",
    "clusterTableFolded",
    "clusterTableList",
    "clusterTableList<-",
    "compareKnown",
    "compareKnownStructures",
    "featureInfo",
    "foldrnaCrosslink",
    "getData",
    "getInteractions",
    "getReverseInteractions",
    "group",
    "InputFiles",
    "makeExamplernaCrosslinkDataSet",
    "matrixList",
    "matrixList<-",
    "plotClusterAgreement",
    "plotClusterAgreementHeat",
    "plotCombinedMatrix",
    "plotComparisonArc",
    "plotEnsemblePCA",
    "plotInteractions",
    "plotInteractionsAverage",
    "plotMatrices",
    "plotMatricesAverage",
    "plotStructure",
    "readNumbers",
    "rnaCrosslinkDataSet",
    "rnaCrosslinkQC",
    "rnas",
    "rnaSize",
    "sampleNames",
    "sampleTable",
    "topInteracters",
    "topInteractions",
    "topTranscripts",
    "trimClusters"
  ],
  "_help": [
    {
      "page": "clusterGrangesList",
      "title": "clusterGrangesList",
      "topics": [
        "clusterGrangesList",
        "clusterGrangesList,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "clusterGrangesList_set",
      "title": "clusterGrangesList<-",
      "topics": [
        "clusterGrangesList<-",
        "clusterGrangesList<-,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "clusterNumbers",
      "title": "clusterNumbers",
      "topics": [
        "clusterNumbers",
        "clusterNumbers,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "clusterrnaCrosslink",
      "title": "clusterrnaCrosslink",
      "topics": [
        "clusterrnaCrosslink",
        "clusterrnaCrosslink,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "clusterTableFolded",
      "title": "clusterTableFolded",
      "topics": [
        "clusterTableFolded",
        "clusterTableFolded,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "clusterTableList",
      "title": "clusterTableList",
      "topics": [
        "clusterTableList",
        "clusterTableList,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "clusterTableList_set",
      "title": "clusterTableList<-",
      "topics": [
        "clusterTableList<-",
        "clusterTableList<-,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "compareKnown",
      "title": "compareKnown",
      "topics": [
        "compareKnown",
        "compareKnown,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "compareKnownStructures",
      "title": "compareKnownStructures",
      "topics": [
        "compareKnownStructures",
        "compareKnownStructures,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "featureInfo",
      "title": "featureInfo",
      "topics": [
        "featureInfo",
        "featureInfo,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "findBasePairsRNAcoFold2",
      "title": "findBasePairsRNAcoFold2",
      "topics": [
        "findBasePairsRNAcoFold2"
      ]
    },
    {
      "page": "findBasePairsRNAfold",
      "title": "findBasePairsRNAfold",
      "topics": [
        "findBasePairsRNAfold"
      ]
    },
    {
      "page": "findBasePairsRNAfold2",
      "title": "findBasePairsRNAfold2",
      "topics": [
        "findBasePairsRNAfold2"
      ]
    },
    {
      "page": "foldrnaCrosslink",
      "title": "foldrnaCrosslink",
      "topics": [
        "foldrnaCrosslink",
        "foldrnaCrosslink,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "getAdjacancyMat",
      "title": "getAdjacancyMat",
      "topics": [
        "getAdjacancyMat"
      ]
    },
    {
      "page": "getClusterClusterShortRangeWhole",
      "title": "getClusterClusterShortRangeWhole",
      "topics": [
        "getClusterClusterShortRangeWhole"
      ]
    },
    {
      "page": "getData",
      "title": "getData",
      "topics": [
        "getData",
        "getData,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "getInteractions",
      "title": "getInteractions",
      "topics": [
        "getInteractions",
        "getInteractions,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "getMatrices",
      "title": "getMatrices",
      "topics": [
        "getMatrices"
      ]
    },
    {
      "page": "getReverseInteractions",
      "title": "getReverseInteractions",
      "topics": [
        "getReverseInteractions",
        "getReverseInteractions,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "group",
      "title": "group",
      "topics": [
        "group",
        "group,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "InputFiles",
      "title": "InputFiles",
      "topics": [
        "InputFiles",
        "InputFiles,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "InputToGRanges",
      "title": "InputToGRanges",
      "topics": [
        "InputToGRanges"
      ]
    },
    {
      "page": "makeExamplernaCrosslinkDataSet",
      "title": "makeExamplernaCrosslinkDataSet",
      "topics": [
        "makeExamplernaCrosslinkDataSet"
      ]
    },
    {
      "page": "matrixList",
      "title": "matrixList",
      "topics": [
        "matrixList",
        "matrixList,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "matrixList_set",
      "title": "matrixList",
      "topics": [
        "matrixList<-",
        "matrixList<-,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotClusterAgreement",
      "title": "Plot a heatmap that plots the agreements between replicates after clusterrnaCrosslink has been performed",
      "topics": [
        "plotClusterAgreement",
        "plotClusterAgreement,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotClusterAgreementHeat",
      "title": "Plot a heatmap that plots the agreements between replicates after clusterrnaCrosslink has been performed",
      "topics": [
        "plotClusterAgreementHeat",
        "plotClusterAgreementHeat,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotCombinedMatrix",
      "title": "Plots a contact map of two chosen samples for chosen stages in the analysis, with each chosen sample on separate halves of the contact map",
      "topics": [
        "plotCombinedMatrix",
        "plotCombinedMatrix,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotComparisonArc",
      "title": "plotComparisonArc",
      "topics": [
        "plotComparisonArc",
        "plotComparisonArc,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotEnsemblePCA",
      "title": "plotEnsemblePCA",
      "topics": [
        "plotEnsemblePCA",
        "plotEnsemblePCA,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotInteractions",
      "title": "Plots a contact map of interactions of each sample of an RNA (interactor) on the RNA of interest",
      "topics": [
        "plotInteractions",
        "plotInteractions,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotInteractionsAverage",
      "title": "Plots a contact map of interactions of all samples of an RNA (interactor) on the RNA of interest",
      "topics": [
        "plotInteractionsAverage",
        "plotInteractionsAverage,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotMatrices",
      "title": "Plots a number of contact maps to file of each sample for a stage in the analysis",
      "topics": [
        "plotMatrices",
        "plotMatrices,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotMatricesAverage",
      "title": "plotMatricesAverage",
      "topics": [
        "plotMatricesAverage",
        "plotMatricesAverage,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "plotStructure",
      "title": "plotStructure",
      "topics": [
        "plotStructure",
        "plotStructure,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "printClustersFast",
      "title": "printClustersFast",
      "topics": [
        "printClustersFast"
      ]
    },
    {
      "page": "readNumbers",
      "title": "readNumbers",
      "topics": [
        "readNumbers",
        "readNumbers,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "rnaCrosslinkDataSet",
      "title": "rnaCrosslinkDataSet",
      "topics": [
        "rnaCrosslinkDataSet",
        "rnaCrosslinkDataSet-class"
      ]
    },
    {
      "page": "rnaCrosslinkQC",
      "title": "rnaCrosslinkQC",
      "topics": [
        "rnaCrosslinkQC"
      ]
    },
    {
      "page": "rnas",
      "title": "rnas",
      "topics": [
        "rnas",
        "rnas,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "rnaSize",
      "title": "rnaSize",
      "topics": [
        "rnaSize",
        "rnaSize,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "sampleChimeras",
      "title": "sampleChimeras",
      "topics": [
        "sampleChimeras"
      ]
    },
    {
      "page": "sampleNames",
      "title": "sampleNames",
      "topics": [
        "sampleNames",
        "sampleNames,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "sampleTable",
      "title": "sampleTable",
      "topics": [
        "sampleTable",
        "sampleTable,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "subsetInputList2",
      "title": "subsetInputList2",
      "topics": [
        "subsetInputList2"
      ]
    },
    {
      "page": "swapInputs",
      "title": "swapInputs",
      "topics": [
        "swapInputs"
      ]
    },
    {
      "page": "swapInputs2",
      "title": "swapInputs2",
      "topics": [
        "swapInputs2"
      ]
    },
    {
      "page": "swapInputs3",
      "title": "swapInputs3",
      "topics": [
        "swapInputs3"
      ]
    },
    {
      "page": "topInteracters",
      "title": "topInteracters",
      "topics": [
        "topInteracters",
        "topInteracters,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "topInteractions",
      "title": "topInteractions",
      "topics": [
        "topInteractions",
        "topInteractions,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "topTranscripts",
      "title": "topTranscripts",
      "topics": [
        "topTranscripts",
        "topTranscripts,rnaCrosslinkDataSet-method"
      ]
    },
    {
      "page": "trimClusters",
      "title": "trimClusters",
      "topics": [
        "trimClusters",
        "trimClusters,rnaCrosslinkDataSet-method"
      ]
    }
  ],
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    "pkgconfig",
    "plotly",
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    "progress",
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    "ps",
    "purrr",
    "R4RNA",
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  "_vignettes": [
    {
      "source": "rnaCrosslinkOO.Rmd",
      "filename": "rnaCrosslinkOO.html",
      "title": "rnaCrosslinkOO",
      "author": "Jonathan Price",
      "engine": "knitr::rmarkdown",
      "headings": [
        "rnaCrosslinkOO",
        "The COMRADES experiment",
        "rnaCrosslink data pre-processing",
        "Nextflow pipeline",
        "Nextflow pipeline output",
        "Input for rnaCrosslink-OO",
        "Load the Library",
        "Make the Sample table",
        "Choose RNA",
        "Transript fasta",
        "A set of interactions to compare to (optional)",
        "Reactivities (optional)",
        "Slow Start",
        "rnaCrosslinkQC",
        "Make the Object",
        "Slots / Attributes",
        "Analysis stage",
        "Meta-data",
        "Raw-data and processed data",
        "rnaCrosslinkDataSet - make object",
        "Access the data within the instance",
        "General Acessors",
        "Check Status of Instance",
        "Retreive RNA Size",
        "Retreive Meta-data",
        "Retreive Sample Groups",
        "Retreive Sample Names",
        "Retreive Data in original format",
        "Retreive Contact Matrices",
        "Get Data",
        "Check Interactions",
        "topTranscripts",
        "topInteractors",
        "topInteractions",
        "Get Count Matricies",
        "Clustering",
        "Cluster Numbers",
        "Read numbers in clusters",
        "Cluster Tables",
        "Cluster GRanges",
        "Cluster Trimming",
        "Check Cluster Agreement between replicates",
        "Folding",
        "Other Plots and Functionality",
        "Plotting contact matrices",
        "Identifying domains",
        "",
        "Analyse folds",
        "Ensemble Stats",
        "HotSpots of difference",
        "PCA of ensembl",
        "Plot to strcutures on an arc diagram",
        "Plot one structure",
        "Inter RNA interactions- Plot an interacting partner",
        "Compare to the \"Known\" structure",
        "Make a contact matrix of known / comprative interactions",
        "Compare the Clusters",
        "Plot the overlapping clusters",
        "Compare structures with a set of contacts",
        "Quick start"
      ],
      "created": "2024-02-18 21:19:57",
      "modified": "2024-07-10 16:19:59",
      "commits": 13
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  "_indexed": true,
  "_nocasepkg": "rnacrosslinkoo",
  "_universes": [
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